Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044821 | 0.69 | KMT2A (0.39) | GSK3B | |
| SCHEMBL9044806 | 0.69 | KMT2A (0.39) | GSK3B | |
| SCHEMBL8054205 | 0.66 | PARP1 (0.30) | — | |
| SCHEMBL9197462 | 0.63 | GSK3B (0.47) | GSK3B | |
| SCHEMBL28839351 | 0.62 | KDM4E (0.35) | CRBNGSK3B | |
| SCHEMBL171853 | 0.55 | HDAC8 (0.47) | — | |
| SCHEMBL133284 | 0.55 | HSD17B10 (0.39) | — | |
| Bicarbonate SCHEMBL9375006 | 0.54 | NISCH (0.52) | — | |
| SCHEMBL1129657 | 0.53 | ALDH1A1 (0.39) | — | |
| Water SCHEMBL11883570 | 0.53 | HSD17B10 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156811-A1 | Process for the Preparation of Bosentan | DIPHARMA FRANCIS S.R.L. (IT) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156811-A1 | Process for the Preparation of Bosentan | PAH, HBB, HBZ | CRBN 389/4885GSK3B 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.