Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 19/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048146 | 0.83 | FDPS (0.60) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL3976360 | 0.82 | FDPS (0.57) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL11952578 | 0.78 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8038000 | 0.78 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL9333595 | 0.77 | FDPS (0.61) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8049638 | 0.76 | FDPS (0.61) | FDPSGGPS1PDE3A | |
| SCHEMBL9333367 | 0.75 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL16091938 | 0.75 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL10602953 | 0.75 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8050318 | 0.73 | FDPS (0.45) | FDPSGGPS1PDE3AAGTR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563096-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | claimed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | claimed |
| EP-0563096-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5438048-A | Used for treatment of disorders related to metabolism of calcium and other bivalent metals; treats bone cancer, urolithiasis, rheumatoid arthritis, bone infection and bone degradation | LEIRAS OY (FI) | 1995-08-01 | — | — | US | disclosed |
| EP-0563096-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |