Menthone

Menthone

SCHEMBL80560

CC1CCC(C(C)C)C(=O)C1.OCC(O)CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TLR4 O00206 2/20 0.32
PER2 O15055 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rel-Menthone SCHEMBL80559 1.00 NPC1 (0.33) NPC1L3MBTL1TLR4PER2ALDH1A1
Menthone SCHEMBL1031003 1.00 NPC1 (0.33) NPC1L3MBTL1TLR4PER2ALDH1A1
Rel-Menthone SCHEMBL3636289 0.95 NPC1 (0.34) NPC1L3MBTL1
Menthone SCHEMBL3636290 0.95 NPC1 (0.34) NPC1L3MBTL1
Rel-Menthone SCHEMBL111746 0.89 LMNA (0.32) LMNA
Menthone SCHEMBL3652908 0.89 LMNA (0.32) LMNA
Rel-Menthone SCHEMBL5712928 0.87 TRPM8 (0.53) ALDH1A1LMNA
Rel-Menthone SCHEMBL21711 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4
Menthone SCHEMBL4395963 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4
Menthone SCHEMBL13255148 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3252 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116942721-B Nasal cavity nursing liquid based on garlicin 湖南省天香生物科技有限责任公司 2024-06-28 CN claimed
CN-118021715-A Temperature-sensitive antipyretic gel and preparation method thereof 浙江蓝禾医疗用品有限公司 2024-05-14 CN claimed
CN-117956976-A Nonaqueous oral composition 狮王株式会社 2024-04-30 CN claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
CN-110869365-B Cooling composition 弗门尼舍有限公司 2024-03-29 CN claimed
CN-113546137-B A pharmaceutical composition for treating or preventing oral diseases 四川济生堂药业有限公司 2024-03-01 CN claimed
CN-117615798-A Composition for combating malodour 西姆莱斯股份公司 2024-02-27 CN claimed
CN-117582375-A Antipruritic composition and preparation method and application thereof 深圳杉海创新技术有限公司 2024-02-23 CN claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 US claimed
US-20240041726-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. 2024-02-08 US claimed
WO-2002091849-A1 A CHEWING GUM HAVING PROLONGED SENSORY BENEFITS WM. WRIGLEY JR. COMPANY (US) 2002-11-21 WO claimed
WO-2002083192-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO claimed
EP-1250941-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP claimed
WO-2002045714-A1 DRUG FORMULATION HAVING IMPROVED ORAL TOLERABILITY THE PROCTER & GAMBLE COMPANY (US) 2002-06-13 WO claimed
US-20020012640-A1 Cosmetic composition for stressed skin under extreme conditions JEFFERIES FINANCE LLC, AS COLLATERAL AGENT 2002-01-31 US claimed
WO-2001095728-A1 COSMETIC COMPOSITION FOR STRESSED SKIN UNDER EXTREME CONDITIONS FD MANAGEMENT, INC. (US) 2001-12-20 WO claimed
EP-1121927-A2 A composition causing different skin sensations Takasago International Corporation (JP) 2001-08-08 EP claimed
CN-1275887-A Chewing gum containing physiological cooling agents WRIGLEY W M JUN CO (US) 2000-12-06 CN claimed
EP-1014805-A1 CHEWING GUM CONTAINING PHYSIOLOGICAL COOLING AGENTS WM. WRIGLEY JR. COMPANY (US) 2000-07-05 EP claimed
WO-1999013734-A1 CHEWING GUM CONTAINING PHYSIOLOGICAL COOLING AGENTS WM. WRIGLEY JR. COMPANY (US) 1999-03-25 WO claimed