Menthone

Menthone

SCHEMBL1031003

CC(C)[C@@H]1CC[C@@H](C)CC1=O.OCC(O)CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TLR4 O00206 2/20 0.32
PER2 O15055 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Menthone SCHEMBL80560 1.00 NPC1 (0.33) NPC1L3MBTL1TLR4PER2ALDH1A1
Rel-Menthone SCHEMBL80559 1.00 NPC1 (0.33) NPC1L3MBTL1TLR4PER2ALDH1A1
Rel-Menthone SCHEMBL3636289 0.95 NPC1 (0.34) NPC1L3MBTL1
Menthone SCHEMBL3636290 0.95 NPC1 (0.34) NPC1L3MBTL1
Rel-Menthone SCHEMBL111746 0.89 LMNA (0.32) LMNA
Menthone SCHEMBL3652908 0.89 LMNA (0.32) LMNA
Rel-Menthone SCHEMBL5712928 0.87 TRPM8 (0.53) ALDH1A1LMNA
Rel-Menthone SCHEMBL21711 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4
Menthone SCHEMBL4395963 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4
Menthone SCHEMBL13255148 0.86 TLR4 (0.39) NPC1L3MBTL1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116590100-A Functional cool essence and preparation method thereof 四川味欣食品科技有限公司 2023-08-15 CN claimed
CN-116376636-A Refreshing mint essence and preparation method thereof 四川味欣食品科技有限公司 2023-07-04 CN claimed
CN-110603025-B Cosmetic composition with antioxidant properties 上海百雀羚生物科技有限公司 2023-06-02 CN claimed
US-20230059747-A1 A COOLING PREPARATION SYMRISE AG (DE) 2023-02-23 US claimed
CN-115531434-A Mint essence with good taste 深圳市优绿信生物科技有限公司 2022-12-30 CN claimed
CN-113993500-A Cool preparation 德国德之馨香精香料公司 2022-01-28 CN claimed
CN-108272862-B Pudilan oral spray and preparation method thereof 济川药业集团有限公司 2021-01-05 CN claimed
EP-3675804-A2 COSMETIC COMPOSITIONS HAVING ANTIOXIDANT PROPERTIES Shanghai Pechoin Biotech Co., Ltd (CN) 2020-07-08 EP claimed
US-20200188265-A1 COSMETIC COMPOSITIONS HAVING ANTIOXIDANT PROPERTIES SHANGHAI PECHPOIN BIOTECH CO., LTD (CN) 2020-06-18 US claimed
CN-110603025-A Cosmetic composition with antioxidant properties 上海百雀羚生物科技有限公司 2019-12-20 CN claimed
CN-106281680-A A kind of quick-fried pearl of Herba Menthae cigarette cool taste Mint Essence and preparation method and application 山东中烟工业有限责任公司 2017-01-04 CN claimed
WO-2016166038-A1 WHITENING COMPOSITIONS SYMRISE AG (DE) 2016-10-20 WO claimed
EP-3081207-A1 WHITENING COMPOSITIONS Symrise AG (DE) 2016-10-19 EP claimed
CN-105831611-A Improved low-temperature meat product composition 江凯 2016-08-10 CN claimed
US-20150190326-A1 COSMETIC COMPOSITIONS SYMRISE AG (DE) 2015-07-09 US claimed
CN-104661633-A Cosmetic compositions SYMRISE AG 2015-05-27 CN claimed
WO-2014023640-A2 COSMETIC COMPOSITIONS SYMRISE AG (DE) 2014-02-13 WO claimed
EP-2695597-A1 Cosmetic compositions Symrise AG (DE) 2014-02-12 EP claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230059747-A1 A COOLING PREPARATION GPX4, HTR3C, ADH1C NPC1 2643/4885L3MBTL1 4176/4885TLR4 2099/4885
US-20150190326-A1 COSMETIC COMPOSITIONS CUTA, MITF, TYR NPC1 1378/4885L3MBTL1 4626/4885TLR4 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.