Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601079 | 0.88 | MEN1 (0.36) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8060949 | 0.85 | MEN1 (0.32) | LMNANPC1RAB9ASMN1; SMN2POLB | |
| Butadiene SCHEMBL8466562 | 0.84 | MEN1 (0.33) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8057554 | 0.84 | GAA (0.39) | LMNANPC1RAB9AHPGDPOLB | |
| SCHEMBL8060999 | 0.83 | MEN1 (0.30) | NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8678439 | 0.82 | MEN1 (0.33) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8465654 | 0.82 | MEN1 (0.33) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8057508 | 0.82 | MEN1 (0.30) | — | |
| SCHEMBL8063166 | 0.81 | GAA (0.41) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8057584 | 0.80 | SIGMAR1 (0.34) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822937-B1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | DOW CHEMICAL CO (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5491246-A | Synthesis of group 4 metal diene complexes | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |