Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053802 | 0.89 | SIGMAR1 (0.59) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL7975188 | 0.85 | AOC3 (0.55) | LMNAACHEHDAC1AOC3TAAR1 | |
| SCHEMBL8088764 | 0.81 | SIGMAR1 (0.52) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL6911972 | 0.80 | PYCR1 (0.55) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL8818924 | 0.79 | ACHE (0.60) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL6910453 | 0.79 | SIGMAR1 (0.52) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL8041553 | 0.78 | TACR1 (0.63) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL6910518 | 0.77 | SIGMAR1 (0.50) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL6911907 | 0.77 | ACHE (0.50) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL12201774 | 0.76 | SIGMAR1 (0.56) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | claimed |
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | disclosed |