Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053802 | 0.84 | SIGMAR1 (0.59) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| SCHEMBL9446202 | 0.82 | TACR1 (0.64) | TACR1CYP2D6SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6906283 | 0.79 | CYP2D6 (0.65) | TACR1SIGMAR1LMNANR1I2ADRA2A | |
| SCHEMBL8056771 | 0.78 | SIGMAR1 (0.56) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL65526 | 0.77 | CYP2D6 (1.00) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL20456391 | 0.77 | CYP2D6 (1.00) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL29354083 | 0.77 | CYP2D6 (1.00) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL29459249 | 0.75 | LMNA (0.97) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL262301 | 0.75 | LMNA (0.97) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 | |
| Butenafine SCHEMBL676912 | 0.75 | LMNA (0.97) | SIGMAR1LMNANR1I2ADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | claimed |
| JP-9255633-A | — | — | None | — | — | JP | disclosed |
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | disclosed |
| JP-H09255633-A | ANTIMYCOTIC AGENT | POLA CHEM IND INC | 1997-09-30 | — | — | JP | disclosed |