Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066440 | 0.91 | FAAH (0.48) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL8056976 | 0.90 | BCHE (0.49) | FAAHRAB9AALDH1A1MAPTBCHE | |
| SCHEMBL8072817 | 0.85 | RAB9A (0.54) | RAB9AALDH1A1BCHECES1 | |
| SCHEMBL8067778 | 0.85 | ALDH1A1 (0.52) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL8067453 | 0.85 | BCHE (0.46) | FAAHRAB9AALDH1A1MAPTBCHE | |
| SCHEMBL8068660 | 0.83 | CCKBR (0.52) | FAAHRAB9AALDH1A1MAPTBCHE | |
| SCHEMBL8902949 | 0.82 | FAAH (0.54) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL8068738 | 0.82 | FAAH (0.56) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL8071083 | 0.82 | FAAH (0.56) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL8071036 | 0.80 | FAAH (0.54) | FAAHRAB9ASMN1; SMN2NLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |