Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073566 | 0.94 | CASP3 (0.44) | CYP19A1CASP3MAPTCYP1A2CYP3A4 | |
| SCHEMBL8058108 | 0.83 | CYP19A1 (0.43) | CYP19A1CASP3MAPTCYP1A2CYP3A4 | |
| SCHEMBL8071414 | 0.82 | MAPT (0.42) | CYP19A1CASP3MAPTCYP1A2CYP3A4 | |
| SCHEMBL8067017 | 0.81 | SMN1; SMN2 (0.48) | CYP19A1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL7824961 | 0.81 | CYP19A1 (0.46) | CYP19A1MAPTCYP1A2AKR1C3LMNA | |
| SCHEMBL7824962 | 0.79 | AKR1C3 (0.51) | CYP19A1MAPTAKR1C3LMNAMEN1 | |
| SCHEMBL8073356 | 0.76 | AKR1C3 (0.47) | CYP19A1MAPTAKR1C3LMNAMEN1 | |
| SCHEMBL7828177 | 0.75 | AKR1C3 (0.47) | MAPTCYP1A2AKR1C3POLBSMN1; SMN2 | |
| SCHEMBL7831300 | 0.75 | SMN1; SMN2 (0.48) | CYP19A1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL22608343 | 0.75 | CYP19A1 (0.56) | CYP19A1MAPTAKR1C3LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |