Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.60 |
| ▸ | ITGAV | P06756 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067444 | 1.00 | ITGB3 (0.60) | ITGB3ITGA2BITGAVPTPN1CHRM2 | |
| SCHEMBL8076479 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8072985 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8071657 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL2728905 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACE | |
| SCHEMBL5727469 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACE | |
| SCHEMBL8073649 | 0.79 | ITGB3 (0.37) | ITGB3ITGA2BITGAV | |
| SCHEMBL2894161 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BPTPN1YAP1 | |
| SCHEMBL2892006 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BPTPN1YAP1 | |
| SCHEMBL6685168 | 0.79 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |