Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.37 |
| ▸ | HRH2 | P25021 | 6/20 | 0.36 |
| ▸ | HRH1 | P35367 | 6/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073128 | 0.93 | HRH2 (0.36) | ITGB3ITGA2BHRH2HRH1ITGAV | |
| SCHEMBL8066212 | 0.90 | PTPN1 (0.37) | ITGB3ITGA2BHRH2HRH1CTSS | |
| SCHEMBL8073645 | 0.85 | HRH2 (0.36) | HRH2HRH1 | |
| SCHEMBL8080722 | 0.85 | HRH2 (0.36) | HRH2HRH1 | |
| SCHEMBL8057985 | 0.84 | HRH2 (0.35) | ITGB3ITGA2BHRH2HRH1 | |
| SCHEMBL8066147 | 0.84 | ELANE (0.35) | HRH2HRH1 | |
| SCHEMBL2899185 | 0.80 | GPR119 (0.40) | HRH2HRH1 | |
| SCHEMBL2899181 | 0.80 | GPR119 (0.40) | HRH2HRH1 | |
| SCHEMBL8067444 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL8057786 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |