Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076479 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BITGAVYAP1HRH2 | |
| SCHEMBL8057786 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BITGAVYAP1CHRM2 | |
| SCHEMBL8067444 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BITGAVYAP1CHRM2 | |
| SCHEMBL8076280 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8073128 | 0.80 | HRH2 (0.36) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL2728593 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2BYAP1HRH2HRH1 | |
| SCHEMBL5892285 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2BYAP1HRH2HRH1 | |
| SCHEMBL2897695 | 0.80 | HRH2 (0.42) | ITGB3ITGA2BYAP1HRH2HRH1 | |
| SCHEMBL2897693 | 0.80 | HRH2 (0.42) | ITGB3ITGA2BYAP1HRH2HRH1 | |
| SCHEMBL4937967 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |