Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055177 | 0.88 | GRM4 (0.33) | EGLN1 | |
| SCHEMBL8042371 | 0.86 | EGLN1 (0.33) | EGLN1 | |
| SCHEMBL3608280 | 0.72 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL31347383 | 0.66 | EGLN1 (0.38) | EGLN1 | |
| SCHEMBL19127825 | 0.63 | LTA4H (0.37) | TSHR | |
| SCHEMBL8042375 | 0.62 | EGLN1 (0.40) | EGLN1 | |
| SCHEMBL19126978 | 0.62 | CDK1 (0.38) | — | |
| SCHEMBL12352091 | 0.61 | EGLN1 (0.33) | EGLN1TSHR | |
| SCHEMBL22120146 | 0.60 | GAA (0.37) | TSHR | |
| SCHEMBL2282478 | 0.58 | NQO2 (0.33) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156811-A1 | Process for the Preparation of Bosentan | DIPHARMA FRANCIS S.R.L. (IT) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156811-A1 | Process for the Preparation of Bosentan | PAH, HBB, HBZ | EGLN1 314/4885TSHR 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.