Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347383 | 0.84 | EGLN1 (0.38) | EGLN1NQO2 | |
| SCHEMBL8042375 | 0.80 | EGLN1 (0.40) | EGLN1NQO2 | |
| SCHEMBL10392936 | 0.79 | MB (0.33) | NQO2SRCERN1HKDC1 | |
| SCHEMBL2282478 | 0.74 | NQO2 (0.33) | EGLN1NQO2SRCERN1HKDC1 | |
| SCHEMBL12766702 | 0.74 | ERN1 (0.38) | EGLN1ALDH1A1ERN1 | |
| SCHEMBL28744682 | 0.73 | NQO2 (0.39) | NQO2NPSR1ALDH1A1 | |
| SCHEMBL4446227 | 0.73 | ALDH1A1 (0.41) | NQO2ALDH1A1MAPT | |
| SCHEMBL2842749 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL8058009 | 0.72 | EGLN1 (0.36) | EGLN1 | |
| SCHEMBL11100217 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835216-B2 | For preventing free radical-mediated cellular damage or disruption; as oxidation inhibitors as additives to fuels, lubricants, rubber, polymers, chemicals, solvents and foodstuffs | VANDERBILT UNIVERSITY | 2004-12-28 | — | — | US | claimed |
| US-20130004972-A1 | METHOD FOR THE DETECTION OF PREDIABETES | FUKUOKA UNIVERSITY (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20130004972-A1 | METHOD FOR THE DETECTION OF PREDIABETES | FUKUOKA UNIVERSITY (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20100041683-A1 | NOVEL CHAIN-BREAKING ANTIOXIDANTS | PRATT DEREK A | 2010-02-18 | — | — | US | disclosed |
| US-7547709-B2 | Chain-breaking antioxidants | VANDERBILT UNIVERSITY (US) | 2009-06-16 | — | — | US | disclosed |
| US-20050065174-A1 | Novel chain-breaking antioxidants | VANDERBILT UNIVERSITY | 2005-03-24 | — | — | US | disclosed |
| US-6835216-B2 | For preventing free radical-mediated cellular damage or disruption; as oxidation inhibitors as additives to fuels, lubricants, rubber, polymers, chemicals, solvents and foodstuffs | VANDERBILT UNIVERSITY | 2004-12-28 | — | — | US | disclosed |
| US-20020143025-A1 | Novel chain-breaking antioxidants | VANDERBILT UNIVERSITY | 2002-10-03 | — | — | US | disclosed |
| WO-2002000683-A2 | NOVEL CHAIN-BREAKING ANTIOXIDANTS | VANDERBILT UNIVERSITY (US) | 2002-01-03 | — | — | WO | disclosed |
| US-4729987-A | Insecticidal O,O-diethyl-O-(2-(1,1-dimethylethyl)-5-pyrimidinyl)-phosphorothioate | THE DOW CHEMICAL COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4654329-A | Insecticidal, miticidal or nematocidal phosphorus esters of 5-pyrimidinols | THE DOW CHEMICAL COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4429125-A | INSECTICIDES FOR APPLICATION TO SOILS | THE DOW CHEMICAL CO. (US) | 1984-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065174-A1 | Novel chain-breaking antioxidants | TTPA, GPX4, PNPO | EGLN1 1895/4885NQO2 1387/4885NPSR1 4726/4885 |
| US-20100041683-A1 | NOVEL CHAIN-BREAKING ANTIOXIDANTS | TTPA, GPX4, PNPO | EGLN1 1895/4885NQO2 1387/4885NPSR1 4726/4885 |
| US-20020143025-A1 | Novel chain-breaking antioxidants | TTPA, GPX4, PNPO | EGLN1 1895/4885NQO2 1387/4885NPSR1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.