Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78113 | 0.85 | TSHR (0.48) | NPY2RL3MBTL1KMT2ACYP3A4ICMT | |
| SCHEMBL79839 | 0.84 | KMT2A (0.38) | NPY2RKMT2ACYP3A4ICMTGMNN | |
| SCHEMBL79837 | 0.84 | KMT2A (0.38) | NPY2RKMT2ACYP3A4ICMTGMNN | |
| SCHEMBL78353 | 0.79 | ALDH1A1 (0.40) | KMT2ACYP1A2POLBHSD17B10ALDH1A1 | |
| SCHEMBL78628 | 0.78 | NPY2R (0.52) | NPY2RL3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL11343622 | 0.78 | KMT2A (0.37) | NPY2RL3MBTL1KMT2ACYP1A2POLB | |
| SCHEMBL77536 | 0.78 | CYP1A2 (0.37) | NPY2RKMT2ACYP1A2POLBHSD17B10 | |
| SCHEMBL79386 | 0.78 | CYP1A2 (0.37) | NPY2RKMT2ACYP1A2POLBHSD17B10 | |
| SCHEMBL80086 | 0.77 | MTNR1A (0.42) | NPY2RKMT2AMEN1NPC1RAB9A | |
| SCHEMBL78291 | 0.77 | RIPK1 (0.36) | NPY2RKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618162-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2012-05-17 | — | — | US | disclosed |
| US-8129428-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090068242-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2009-03-12 | — | — | US | disclosed |
| EP-0010580-B1 | 2-(1-METHYL-PROPYN-2-YL-THIO)-PHENYL-N-METHYLCARBAMATE, PROCESS FOR ITS PREPARATION AND ITS USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4239775-A | 2-(1-Methylpropyn-2-yl-thio)-phenyl-N-methylcarbamate and its use for combating pests of the Acarina order | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0010580-A1 | 2-(1-Methyl-propyn-2-yl-thio)-phenyl-N-methylcarbamate, process for its preparation and its use in combating pests | BASF Aktiengesellschaft (DE) | 1980-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068242-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | ACHE, BCHE, CHAT | NPY2R 2156/4885L3MBTL1 643/4885KMT2A 309/4885 |
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | ACHE, BCHE, CHAT | NPY2R 2156/4885L3MBTL1 643/4885KMT2A 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.