Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073042 | 0.92 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL8068255 | 0.88 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL8068125 | 0.86 | FOLH1 (0.42) | FOLH1MTNR1AMTNR1BPSMB5EPOR | |
| SCHEMBL7598385 | 0.83 | TRPM8 (0.44) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL8069618 | 0.82 | CTSS (0.42) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL21460902 | 0.82 | MAPT (0.51) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL21460905 | 0.82 | MAPT (0.51) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL15802598 | 0.80 | MAPT (0.46) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7594433 | 0.79 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7598318 | 0.79 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1MAPTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |