SCHEMBL8059192

SCHEMBL8059192

c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(CP(C3CCCCC3)C3CCCCC3)ccc3ccccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
MPI P34949 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043515 0.86 ALDH1A1 (0.33) ALDH1A1MAPTMPICYP1A2CYP2D6
SCHEMBL7544297 0.82 ALDH1A1 (0.35) ALDH1A1MAPTMPICYP1A2CYP2D6
SCHEMBL9014995 0.79 WDR5 (0.33) ALDH1A1MAPTHSD17B10
SCHEMBL8059204 0.79 ACP3 (0.33) ALDH1A1MAPTMPICYP1A2CYP2D6
SCHEMBL8832750 0.78 DRD2 (0.31) ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL8056040 0.78 ACP3 (0.35) ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL9058987 0.77 ALDH1A1 (0.42) ALDH1A1MAPTCYP1A2HIF1AHSD17B10
SCHEMBL8056414 0.76 MAPT (0.31) MAPT
SCHEMBL3109226 0.76 KDM1A (0.34) ALDH1A1MAPTMPICYP1A2CYP2D6
SCHEMBL5107 0.76 ALDH1A1 (0.44) ALDH1A1MAPTCYP1A2HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704449-B1 Process for the preparation of diphosphanes CELANESE CHEM EUROPE GMBH (DE) 2000-05-24 EP disclosed
US-5696296-A Diphosphines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
EP-0704449-A1 Diphosphanes and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed