SCHEMBL8043515

SCHEMBL8043515

c1ccc(P(Cc2ccc3ccccc3c2-c2c(CP(C3CCCCC3)C3CCCCC3)ccc3ccccc23)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HIF1A Q16665 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.31
EPHX1 P07099 1/20 0.30
MAPT P10636 1/20 0.30
MPI P34949 1/20 0.30
GAA P10253 1/20 0.30
PKM P14618 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8832750 0.90 DRD2 (0.31) ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9
SCHEMBL8059192 0.86 ALDH1A1 (0.31) ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9
SCHEMBL3955072 0.83 ALDH1A1 (0.39) ALDH1A1HIF1AHSD17B10MAPT
SCHEMBL29447338 0.83 ALDH1A1 (0.39) ALDH1A1HIF1AHSD17B10MAPT
SCHEMBL8056040 0.83 ACP3 (0.35) ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9
SCHEMBL8059204 0.82 ACP3 (0.33) ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9
SCHEMBL29695262 0.82 ALDH1A1 (0.38) ALDH1A1HIF1AHSD17B10MAPT
Potassium SCHEMBL29695394 0.80 WDR5 (0.37) ALDH1A1HIF1AHSD17B10MAPT
SCHEMBL8055076 0.80 ATM (0.30) ALDH1A1HIF1ACYP1A2CYP2D6CYP2C9
SCHEMBL8055052 0.78 BCHE (0.37) ALDH1A1MAPTGAASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728762-B1 Sulfonated disphosphanes and a process for their preparation CELANESE CHEM EUROPE GMBH (DE) 2000-05-24 EP disclosed
EP-0704449-B1 Process for the preparation of diphosphanes CELANESE CHEM EUROPE GMBH (DE) 2000-05-24 EP disclosed
US-5696296-A Diphosphines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
US-5684182-A Sulfonated diphosphines and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-04 US disclosed
EP-0728762-A1 Sulfonated disphosphanes and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-28 EP disclosed
EP-0704449-A1 Diphosphanes and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed