SCHEMBL8059403

SCHEMBL8059403

Cc1ccccc1S(=O)(=O)c1ccc(O)c(S(=O)(=O)c2ccccc2C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
ALDH1A1 P00352 2/20 0.58
PKM P14618 1/20 0.58
POLB P06746 2/20 0.51
GFER P55789 1/20 0.51
L3MBTL1 Q9Y468 3/20 0.50
HSD11B1 P28845 1/20 0.50
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
DNMT1 P26358 1/20 0.46
MCL1 Q07820 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ABCC9 O60706 1/20 0.44
ABCC8 Q09428 1/20 0.44
KCNJ11 Q14654 1/20 0.44
KCNJ8 Q15842 1/20 0.44
KDM4E B2RXH2 2/20 0.43
NAMPT P43490 1/20 0.42
ESR1 P03372 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046857 0.94 GAA (0.61) GAAALDH1A1PKMPOLBGFER
SCHEMBL28768152 0.84 GAA (0.64) GAAALDH1A1PKMPOLBGFER
SCHEMBL6211399 0.82 GAA (0.60) GAAALDH1A1PKMPOLBGFER
SCHEMBL8057546 0.82 GAA (0.56) GAAALDH1A1PKMPOLBGFER
SCHEMBL6215926 0.82 L3MBTL1 (0.53) GAAALDH1A1PKMPOLBGFER
SCHEMBL8062004 0.80 L3MBTL1 (0.58) GAAALDH1A1PKMPOLBGFER
SCHEMBL8057518 0.80 L3MBTL1 (0.58) GAAALDH1A1PKMPOLBGFER
SCHEMBL8046908 0.80 ALDH1A1 (0.70) GAAALDH1A1PKMPOLBGFER
SCHEMBL8062016 0.80 ALDH1A1 (0.70) GAAALDH1A1PKMPOLBGFER
SCHEMBL8527509 0.80 GAA (0.51) GAAALDH1A1PKMPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0706997-B1 Sulfonyl compound and thermal-sensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1998-03-11 EP claimed
EP-0706997-A1 Sulfonyl compound and thermal-sensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1996-04-17 EP claimed
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0706997-B1 Sulfonyl compound and thermal-sensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1998-03-11 EP disclosed
US-5705452-A AS DEVELOPER; HIGH SENSITIVITY, LOW BACKGROUND BLUSH DURING STORAGE, RESISTANCE TO HEAT, MOISTURE, PLASTICIZER SANKO HAIHATSU KAGAKU KENKYUSHO (JP) 1998-01-06 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed
EP-0706997-A1 Sulfonyl compound and thermal-sensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1996-04-17 EP disclosed