SCHEMBL8059768

SCHEMBL8059768

CCCN(C(=O)Cl)C(C)CC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 3/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPK1 P28482 1/20 0.30
FDPS P14324 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059643 0.82 TSHR (0.35) CA12CA2CA9TSHRALDH1A1
SCHEMBL8059662 0.82 ALDH1A1 (0.33) TSHRALDH1A1LMNAMAPTSMN1; SMN2
Bromide SCHEMBL9052849 0.80 TSHR (0.33) CA12CA2CA9TSHRALDH1A1
SCHEMBL12656337 0.80 FDPS (0.35) CA12CA2CA9TSHRALDH1A1
SCHEMBL497599 0.80 CA12 (0.33) CA12CA2CA9TSHRALDH1A1
SCHEMBL25123808 0.79 FAAH (0.32)
SCHEMBL497598 0.78 CA12 (0.32) CA12CA2CA9TSHRMAPK1
SCHEMBL2825332 0.78 CA2 (0.33) CA12CA2CA9TSHRMAPK1
SCHEMBL5210955 0.77 ALDH1A1 (0.31) CA12CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL27323419 0.77 CA2 (0.32) CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728750-B1 1-Cycloalkenyltetrazolinones BAYER AGROCHEM KK (JP) 2000-05-17 EP disclosed
US-5776858-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-07-07 US disclosed
US-5747420-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-05 US disclosed
EP-0820994-A1 Tetrazolinones as herbicides and intermediates NIHON BAYER AGROCHEM K.K. (JP) 1998-01-28 EP disclosed
US-5710278-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1998-01-20 US disclosed
US-5654257-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1997-08-05 US disclosed
US-5641727-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0771797-A1 1-Azinyl-tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1997-05-07 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0728750-A1 1-Cycloalkenyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-08-28 EP disclosed
EP-0711761-A1 Tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-05-15 EP disclosed
EP-0708097-A1 Herbicidally active tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-04-24 EP disclosed
EP-0692482-A2 1-pyridyltetrazolinone derivatives NIHON BAYER AGROCHEM K.K. (JP) 1996-01-17 EP disclosed