SCHEMBL805987

SCHEMBL805987

C1=Cc2c(oc3ccc(-c4cccc(-c5cc(-c6cccc(-c7ccc8oc9ccccc9c8c7)c6)cc(-n6c7ccccc7c7ccncc76)c5)c4)cc23)CC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22487614 0.88 PLA2G2A (0.37) PLA2G10PLA2G2APLA2G4A
SCHEMBL804475 0.87 PLA2G2A (0.37) PLA2G10PLA2G2APLA2G4A
SCHEMBL804878 0.87 PLA2G2A (0.37) PLA2G10PLA2G2APLA2G4A
SCHEMBL805988 0.86 PLA2G10 (0.32) PLA2G10PLA2G2APLA2G4A
SCHEMBL21993183 0.85 PLA2G2A (0.38) PLA2G10PLA2G2APLA2G4A
SCHEMBL12175598 0.85 PLA2G2A (0.33) PLA2G10PLA2G2APLA2G4A
SCHEMBL19054200 0.84 PLA2G2A (0.38) PLA2G10PLA2G2APLA2G4A
SCHEMBL12126338 0.84 PLA2G2A (0.35) PLA2G10PLA2G2APLA2G4A
SCHEMBL804799 0.84 NPC1 (0.35) PLA2G10PLA2G2APLA2G4A
SCHEMBL804571 0.83 BTK (0.38) PLA2G10PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120068164-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068164-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EMC2, L1CAM, EMC1 PLA2G10 3693/4885PLA2G2A 2297/4885PLA2G4A 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.