Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811644 | 0.83 | PPARA (0.52) | PPARAPPARGLMNAALDH1A1HPGD | |
| SCHEMBL21059484 | 0.78 | TDP1 (0.36) | PPARAPPARGTSHRKMT2A | |
| SCHEMBL21059487 | 0.78 | TDP1 (0.36) | PPARAPPARGTSHRKMT2A | |
| SCHEMBL6811455 | 0.74 | PPARA (0.71) | PPARAPPARGSLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL8057944 | 0.72 | PPARA (0.45) | PPARAPPARGSLC6A4LMNAALDH1A1 | |
| SCHEMBL586226 | 0.69 | SMN1; SMN2 (0.51) | PPARAPPARGLMNAALDH1A1HPGD | |
| SCHEMBL28673209 | 0.68 | BMP1 (0.35) | PPARAPPARGALDH1A1HPGDKDM4E | |
| SCHEMBL28673207 | 0.68 | BMP1 (0.35) | PPARAPPARGALDH1A1HPGDKDM4E | |
| SCHEMBL6744505 | 0.67 | CES2 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2RXFP1 | |
| SCHEMBL5883770 | 0.66 | CES2 (0.61) | ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046213-A | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives | PFIZER INC. (US) | 2000-04-04 | — | — | US | disclosed |