Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811455 | 0.76 | PPARA (0.71) | PPARAPPARGSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL586226 | 0.73 | SMN1; SMN2 (0.51) | PPARAPPARGABCB1SMN1; SMN2MAPT | |
| SCHEMBL6962227 | 0.72 | ACHE (0.50) | SMN1; SMN2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL8059986 | 0.72 | PPARA (0.41) | PPARAPPARGABCB1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9720571 | 0.72 | HMGCR (0.56) | TAS1R3TAS1R1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL6811644 | 0.69 | PPARA (0.52) | PPARAPPARGSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7953584 | 0.67 | HSP90AB1 (0.45) | SMN1; SMN2MAPTL3MBTL1LMNAHTT | |
| SCHEMBL13284211 | 0.67 | HMGCR (0.68) | SMN1; SMN2MAPTL3MBTL1HTTALDH1A1 | |
| SCHEMBL29254632 | 0.67 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTL3MBTL1LMNAHTT | |
| SCHEMBL31650785 | 0.66 | CES2 (0.44) | LMNAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046213-A | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives | PFIZER INC. (US) | 2000-04-04 | — | — | US | disclosed |