Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.72 |
| ▸ | GART | P22102 | 6/20 | 0.70 |
| ▸ | FPGS | Q05932 | 2/20 | 0.64 |
| ▸ | DHFR | P00374 | 3/20 | 0.59 |
| ▸ | ATIC | P31939 | 4/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.54 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12704421 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL258465 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL8061 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL29616598 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL13418310 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL3199681 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL5829838 | 0.96 | SOST (0.66) | SOSTGARTFPGSDHFRATIC | |
| Tetrahydrofolate SCHEMBL18703989 | 0.94 | SOST (0.82) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL11475679 | 0.93 | SOST (0.62) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL8160135 | 0.93 | SOST (0.71) | SOSTGARTFPGSDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007756-A1 | COMPOUND AND USE THEREOF | COHERENT BIOPHARMA SUZHOU LTD (CN) | 2026-01-08 | — | — | US | claimed |
| EP-4665861-A1 | USE OF TANDEM FACIAL AMPHIPHILES FOR PROTEIN EXPRESSION | Nuclera Ltd (GB) | 2025-12-24 | — | — | EP | claimed |
| US-20250146041-A1 | METHODS FOR CELL FREE PROTEIN SYNTHESIS AND POST TRANSLATIONAL MODIFICATION OF THE EXPRESSED PROTEINS | NUCLERA LTD (GB) | 2025-05-08 | — | — | US | claimed |
| EP-4512426-A1 | COMPOUND AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2025-02-26 | — | — | EP | claimed |
| EP-4479547-A2 | METHODS FOR CELL FREE PROTEIN SYNTHESIS AND POST TRANSLATIONAL MODIFICATION OF THE EXPRESSED PROTEINS | Nuclera Ltd (GB) | 2024-12-25 | — | — | EP | claimed |
| US-20240415837-A1 | PHARMACOLOGIC MODULATION OF 5-FLUOROURACIL BY FOLINIC ACID AND VITAMIN B6 FOR THE TREATMENT OF PATIENTS WITH CARCINOMA | MACHOVER DAVID (FR) | 2024-12-19 | — | — | US | claimed |
| US-20240398857-A1 | COMPOSITIONS FOR MANAGEMENT OF HPV (HUMAN PAPILLOMA VIRUS) INFECTIONS | PAPILLEX INC. (CA) | 2024-12-05 | — | — | US | claimed |
| CN-119050321-A | In-situ nitrogen-doped silicon-carbon composite material, and preparation method and application thereof | 山东能源集团有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-119031938-A | Compounds and uses | 同宜医药（苏州）有限公司 | 2024-11-26 | — | — | CN | claimed |
| US-20240344241-A1 | PROTEINACEOUS MOLECULES AND USES THEREFOR | THE UNIVERSITY OF TOKYO (JP) | 2024-10-17 | — | — | US | claimed |
| US-5800979-A | Gas chromatography/mass spectrometric determination of folic acid coenzymes | KOLHOUSE J FRED (US) | 1998-09-01 | — | — | US | claimed |
| WO-1998019690-A1 | METHOD FOR TREATING ALZHEIMER'S DISEASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-14 | — | — | WO | claimed |
| EP-0813510-A1 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA, Arthur M. (US) | 1997-12-29 | — | — | EP | claimed |
| WO-1996027572-A1 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA ARTHUR M (US) | 1996-09-12 | — | — | WO | claimed |
| US-5446156-A | Mixing water soluble carboxylic or hydrohalic acid with aqueous solution having dissolved ammonium or alkali metal salt of tetrahydrofoic acid derivative, adding alkaline metal salts, precipitation, acidification again, separation of solid | SAPEC S.A. FINE CHEMICALS (CH) | 1995-08-29 | — | — | US | claimed |
| US-5332815-A | Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid | SAPEC S.A. FINE CHEMICALS (CH) | 1994-07-26 | — | — | US | claimed |
| EP-0548895-A2 | Process for the preparation of pure diasteroisomers of tetrahydrofolates | SAPEC S.A. FINE CHEMICALS (CH) | 1993-06-30 | — | — | EP | claimed |
| EP-0535710-A1 | Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid | SAPEC S.A. FINE CHEMICALS (CH) | 1993-04-07 | — | — | EP | claimed |
| EP-0314720-A1 | PROCESS FOR SEPARATION OF FOLINIC ACIDS | EPROVA Aktiengesellschaft (CH) | 1989-05-10 | — | — | EP | claimed |
| WO-1988008844-A1 | PROCESS FOR SEPARATION OF FOLINIC ACIDS | EPROVA AG (CH) | 1988-11-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007756-A1 | COMPOUND AND USE THEREOF | FOLH1, TRPV6, FOLR1 | SOST 2253/4885GART 4075/4885FPGS 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.