Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.72 |
| ▸ | GART | P22102 | 6/20 | 0.70 |
| ▸ | FPGS | Q05932 | 2/20 | 0.64 |
| ▸ | DHFR | P00374 | 3/20 | 0.59 |
| ▸ | ATIC | P31939 | 4/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.54 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12704421 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL8061 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL8060 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL29616598 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL13418310 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL3199681 | 1.00 | SOST (0.72) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL5829838 | 0.96 | SOST (0.66) | SOSTGARTFPGSDHFRATIC | |
| Tetrahydrofolate SCHEMBL18703989 | 0.94 | SOST (0.82) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL11475679 | 0.93 | SOST (0.62) | SOSTGARTFPGSDHFRATIC | |
| SCHEMBL8160135 | 0.93 | SOST (0.71) | SOSTGARTFPGSDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622913-B2 | Folate salts for medical use | APROFOL AG (CH) | 2026-05-12 | — | — | US | claimed |
| US-12318395-B2 | Ethinyl estradiol-β-cyclodextrin complex and process for preparing thereof | LABORATORIOS LEON FARMA, S.A. (ES) | 2025-06-03 | — | — | US | claimed |
| US-12138266-B2 | Folate preparations | APROFOL AG (CH) | 2024-11-12 | — | — | US | claimed |
| US-20230277544-A1 | FOLATE SALTS FOR MEDICAL USE | APROFOL AG (CH) | 2023-09-07 | — | — | US | claimed |
| US-20230158029-A1 | FOLATE COMPOSITIONS | APROFOL AG (CH) | 2023-05-25 | — | — | US | claimed |
| EP-4114399-A1 | FOLATE PREPARATIONS FOR THE TREATMENT OF OCULAR DISEASES | Aprofol AG (CH) | 2023-01-11 | — | — | EP | claimed |
| CN-115427046-A | Folic acid substance preparation for treating eye diseases | 阿普罗福尔公司 | 2022-12-02 | — | — | CN | claimed |
| US-20220279831-A1 | COMPOSITIONS, KITS AND METHODS FOR NUTRITION SUPPLEMENTATION | EXELTIS FRANCE (FR) | 2022-09-08 | — | — | US | claimed |
| WO-2021175740-A1 | FOLATE PREPARATIONS FOR THE TREATMENT OF OCULAR DISEASES | APROFOL AG (CH) | 2021-09-10 | — | — | WO | claimed |
| EP-3875094-A1 | FOLATE PREPARATIONS FOR THE TREATMENT OF OCULAR DISEASES | Aprofol AG (CH) | 2021-09-08 | — | — | EP | claimed |
| US-6254904-B1 | COMPRISING: (6S)-TETRAHYDROFOLIC ACID AND DERIVATIVES AND POLYGLUTAMYL DERIVATIVES; MULTIVITAMIN BREAKFAST FOODS, INFANT FORMULAS, DIETARY SUPPLEMENTS AND ANIMAL FEED PREPARATION | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION | 2001-07-03 | — | — | US | claimed |
| US-6011040-A | Use of tetrahydrofolates in natural stereoisomeric form for the production of a pharmaceutical preparation suitable for influencing the homocysteine level, particularly for assisting the remethylation of homocysteine | EPROVA AG (CH) | 2000-01-04 | — | — | US | claimed |
| US-5997915-A | NATURAL ISOMERS OF TETRAHYDROFOLIC ACID DERIVATIVES | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1999-12-07 | — | — | US | claimed |
| EP-0877563-A4 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | UNIV SOUTH ALABAMA (US) | 1999-06-09 | — | — | EP | claimed |
| EP-0898965-A2 | Use of tetrahydrofolates for modulating the homocysteine level | EPROVA Aktiengesellschaft (CH) | 1999-03-03 | — | — | EP | claimed |
| CN-1205206-A | Use of natural stereoisomers of tetrahydrofolic acid for producing pharmaceutical preparations | EPROVA AG (CH) | 1999-01-20 | — | — | CN | claimed |
| EP-0877563-A1 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | South Alabama Medical Science Foundation (US) | 1998-11-18 | — | — | EP | claimed |
| WO-1997027764-A1 | FOOD AND VITAMIN PREPARATIONS CONTAINING THE NATURAL ISOMER OF REDUCED FOLATES | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1997-08-07 | — | — | WO | claimed |
| US-5332815-A | Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid | SAPEC S.A. FINE CHEMICALS (CH) | 1994-07-26 | — | — | US | claimed |
| EP-0535710-A1 | Process for the preparation of alkaline earth metal salts of (6R)-N(10)-formyl-5,6,7,8-tetrahydrofolic acid | SAPEC S.A. FINE CHEMICALS (CH) | 1993-04-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277544-A1 | FOLATE SALTS FOR MEDICAL USE | FOLR2, FOLR1, MTHFD1 | SOST 1573/4885GART 526/4885FPGS 11/4885 |
| US-12622913-B2 | Folate salts for medical use | FOLR2, FOLR1, MTHFD1 | SOST 2142/4885GART 464/4885FPGS 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.