Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.64 |
| ▸ | CDC25B | P30305 | 9/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066360 | 0.88 | CDC25B (0.59) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL8056899 | 0.85 | PTPN1 (0.54) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL8066039 | 0.84 | CDC25B (0.53) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL9615924 | 0.84 | KDM1A (0.58) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL8056502 | 0.82 | MAPT (0.61) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL8067396 | 0.82 | MAPT (0.61) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL8072543 | 0.80 | PTGS2 (0.51) | PTPN1CDC25BDUSP3KDM1APTGS2 | |
| SCHEMBL8067403 | 0.76 | MAPT (0.60) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL11287831 | 0.74 | KMT2A (0.72) | PTPN1CDC25BDUSP3KMT2AMAPT | |
| SCHEMBL11758890 | 0.73 | KMT2A (0.71) | PTPN1CDC25BDUSP3KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | claimed |