Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 10/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 10/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056899 | 0.94 | PTPN1 (0.54) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8066039 | 0.92 | CDC25B (0.53) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL9615924 | 0.92 | KDM1A (0.58) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8067396 | 0.90 | MAPT (0.61) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8056502 | 0.90 | MAPT (0.61) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8060240 | 0.88 | PTPN1 (0.64) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8072543 | 0.87 | PTGS2 (0.51) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL8067403 | 0.84 | MAPT (0.60) | CDC25BDUSP3PTPN1PTGS2ALDH1A1 | |
| SCHEMBL4115163 | 0.81 | HSD17B10 (0.68) | CDC25BDUSP3PTPN1KDM1APTGS2 | |
| SCHEMBL4110122 | 0.79 | KDM1A (0.76) | CDC25BDUSP3PTPN1KDM1APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | claimed |
| US-5449783-A | Antiinflammatory, analgesic, antiallergic, diuretic agents, anticoagulants | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-09-12 | — | — | US | claimed |
| JP-3173876-A | — | — | None | — | — | JP | disclosed |
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5449783-A | Antiinflammatory, analgesic, antiallergic, diuretic agents, anticoagulants | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0592664-A1 | NOVEL DIPHENYLTHYAZOLE DERIVATIVE | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1994-04-20 | — | — | EP | disclosed |
| JP-H03173876-A | NEW DIPHENYLTHIAZOLE DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1991-07-29 | — | — | JP | disclosed |