Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.51 |
| ▸ | CDC25B | P30305 | 7/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067396 | 1.00 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8067403 | 0.95 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8066360 | 0.90 | CDC25B (0.59) | MAPTALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL8066039 | 0.88 | CDC25B (0.53) | MAPTALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL8056899 | 0.87 | PTPN1 (0.54) | MAPTALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL9615924 | 0.86 | KDM1A (0.58) | MAPTALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL8060240 | 0.82 | PTPN1 (0.64) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8072543 | 0.81 | PTGS2 (0.51) | PTGS2PTPN1CDC25BDUSP3KDM1A | |
| SCHEMBL8056887 | 0.81 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7623998 | 0.77 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | claimed |