Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555306 | 0.86 | HSPA5 (0.40) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5347167 | 0.84 | ELANE (0.53) | HTR2AELANECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29040201 | 0.81 | CALM1 (0.55) | CALM1HTR2ABCL2BCL2L1ELANE | |
| SCHEMBL11410320 | 0.79 | NPC1 (0.47) | CALM1HTR2ABCL2BCL2L1ELANE | |
| SCHEMBL13935792 | 0.79 | ELANE (0.60) | CALM1HTR2AELANECYP1A2CYP3A4 | |
| SCHEMBL6229874 | 0.79 | CALM1 (0.58) | CALM1HTR2ABCL2BCL2L1ELANE | |
| SCHEMBL23280579 | 0.77 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19NR1H2HPGD | |
| SCHEMBL1791522 | 0.77 | ALDH1A1 (0.36) | NR1H2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21380578 | 0.76 | HTR2A (0.44) | CALM1HTR2ABCL2BCL2L1ELANE | |
| SCHEMBL2869740 | 0.76 | ELANE (0.66) | ELANECYP1A2CYP2C9CTSGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589427-B1 | Thermosensitive recording medium | DAINIPPON INK & CHEMICALS (JP) | 1997-03-12 | — | — | EP | claimed |
| EP-1017658-A1 | BENZYL-BIPHENYLS AND ANALOGOUS COMPOUNDS AND THE APPLICATION THEREOF IN ORDER TO TREAT ARTERIOSCLEROSIS AND DYSLIPIDAEMIA | Bayer Aktiengesellschaft (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015487-A1 | BENZYL-BIPHENYLS AND ANALOGOUS COMPOUNDS AND THE APPLICATION THEREOF IN ORDER TO TREAT ARTERIOSCLEROSIS AND DYSLIPIDAEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-01 | — | — | WO | disclosed |