SCHEMBL5410583

SCHEMBL5410583

CCCCCCCCCCCCCCCC(=O)NCC(O)CO

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.58
ASAH1 Q13510 1/20 0.55
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
LMNA P02545 1/20 0.51
MAPK1 P28482 1/20 0.50
HSP90AA1 P07900 1/20 0.50
DNM1 Q05193 1/20 0.49
NAAA Q02083 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13213912 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL14253316 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL9061545 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL968572 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL26393717 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL11310187 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL24339916 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL1004187 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL22067566 1.00 FAAH (0.58) FAAHASAH1MEN1KMT2AKDM4E
SCHEMBL23799216 0.98 FAAH (0.55) FAAHASAH1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987540-B2 Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same GERON CORPORATION (US) 2024-05-21 US disclosed
CN-114901269-A Crystalline solids of 3-palmitoyl-amido-1, 2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same 美国杰龙生物医药公司 2022-08-12 CN disclosed
US-20210147342-A1 CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2021-05-20 US disclosed
US-20210147342-A1 CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2021-05-20 US disclosed
WO-2021086754-A1 CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME GERON CORPORATION (US) 2021-05-06 WO disclosed
WO-2021086754-A1 CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME GERON CORPORATION (US) 2021-05-06 WO disclosed
US-9657296-B2 Modified oligonucleotides for telomerase inhibition GERON CORPORATION (US) 2017-05-23 US disclosed
US-7344868-B2 Method for synthesizing ceramide-type compounds LASSALLE LAURENT 2008-03-18 US disclosed
US-7344868-B2 Method for synthesizing ceramide-type compounds LASSALLE LAURENT 2008-03-18 US disclosed
US-7253296-B2 Acylated aminopropanediols and analogues and therapeutic uses thereof GENFIT (FR) 2007-08-07 US disclosed
US-20060154984-A1 Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof GENFIT (FR) 2006-07-13 US disclosed
US-20060069156-A1 Acylated aminopropanediols and analogues and therapeutic uses thereof GENFIT (FR) 2006-03-30 US disclosed
US-20060035977-A1 Uses of acylated aminopropanediols and sulphur and nitrogen analogues of same f GENTIF (FR) 2006-02-16 US disclosed
EP-1596845-A1 THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF Genfit (FR) 2005-11-23 EP disclosed
EP-1594486-A2 USES OF ACYLATED AMINOPROPANEDIOLS AND SULPHUR AND NITROGEN ANALOGUES OF SAME Genfit (FR) 2005-11-16 EP disclosed
EP-1592660-A1 ACYLATED AMINOPROPANEDIOLS AND ANALOGUES AND THERAPEUTIC USES THEREOF Genfit (FR) 2005-11-09 EP disclosed
WO-2004073593-A2 USE OF ACYLATED AMINOPROPANEDIOLS AND SULPHUR AND NITROGEN ANALOGUES OF SAME FOR DIFFERENT THERAPEUTIC APPLICATIONS GENFIT (FR) 2004-09-02 WO disclosed
WO-2004073698-A1 THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF GENFIT (FR) 2004-09-02 WO disclosed
WO-2004074239-A1 ACYLATED AMINOPROPANEDIOLS AND ANALOGUES AND THERAPEUTIC USES THEREOF GENFIT (FR) 2004-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069156-A1 Acylated aminopropanediols and analogues and therapeutic uses thereof AASDHPPT, ABAT, AADAC FAAH 274/4885ASAH1 409/4885MEN1 3438/4885
US-20060035977-A1 Uses of acylated aminopropanediols and sulphur and nitrogen analogues of same f ASS1, SMURF1, SMURF2 FAAH 412/4885ASAH1 307/4885MEN1 1645/4885
US-11987540-B2 Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same SPTLC3, PLD2, SPTLC2 FAAH 69/4885ASAH1 1234/4885MEN1 2182/4885
US-20210147342-A1 CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME SPTLC3, PLD2, SPTLC2 FAAH 69/4885ASAH1 1234/4885MEN1 2182/4885
US-20060154984-A1 Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof AGPAT5, HAGH, AGPAT2 FAAH 70/4885ASAH1 57/4885MEN1 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.