Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056469 | 0.77 | — | — | |
| SCHEMBL2154184 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL11670395 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL1313097 | 0.67 | BCHE (0.39) | — | |
| SCHEMBL8045037 | 0.67 | USP7 (0.32) | CA1CA2 | |
| SCHEMBL8058227 | 0.66 | — | — | |
| SCHEMBL23029879 | 0.63 | CA1 (0.47) | CA1CA2CA9 | |
| SCHEMBL7705491 | 0.62 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL3827978 | 0.62 | ALDH1A1 (0.45) | — | |
| SCHEMBL7670684 | 0.61 | GPR27 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |