SCHEMBL806315

SCHEMBL806315

Cc1cccc(N(c2cccc(C)c2)c2ccc3ccc4cccc5ccc2c3c45)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HPGD P15428 5/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 6/20 0.40
ACHE P22303 2/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
AHR P35869 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
CYP2A6 P11509 2/20 0.37
MAPT P10636 3/20 0.37
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37
CYP2C9 P11712 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9427757 0.98 ALDH1A1 (0.44) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL1644520 0.97 TDP1 (0.40) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL29555384 0.97 TDP1 (0.40) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL2700479 0.95 ALDH1A1 (0.42) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL22253650 0.92 CYP1A2 (0.40) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL25069433 0.92 SIGMAR1 (0.38) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL1702512 0.92 SIGMAR1 (0.38) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL12856564 0.92 ACHE (0.38) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL8927673 0.92 TDP1 (0.39) ALDH1A1HPGDCYP3A4TDP1HSD17B10
SCHEMBL13333766 0.91 CYP1A2 (0.42) ALDH1A1HPGDCYP3A4TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616883-B1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2017-09-06 EP disclosed
US-8871412-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
US-8871412-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
US-20130177842-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-07-11 US disclosed
US-20130177842-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-07-11 US disclosed
WO-2012036295-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-03-22 WO disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed