SCHEMBL1702512

SCHEMBL1702512

Cc1cccc(N(c2ccccc2)c2ccc3ccc4c(N(c5ccccc5)c5cccc(C)c5)ccc5ccc2c3c54)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.38
ALDH1A1 P00352 6/20 0.37
HPGD P15428 5/20 0.37
TDP1 Q9NUW8 3/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
THRB P10828 2/20 0.37
PKM P14618 1/20 0.37
CYP1A2 P05177 5/20 0.36
NR1I2 O75469 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTR2B P41595 1/20 0.36
CYP51A1 Q16850 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25069433 1.00 SIGMAR1 (0.38) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL2700479 0.97 ALDH1A1 (0.42) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL1644520 0.95 TDP1 (0.40) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL29555384 0.95 TDP1 (0.40) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL19566266 0.93 CYP1A2 (0.41) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL26221657 0.92 TDP1 (0.36) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL13321052 0.92 TDP1 (0.36) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL806315 0.92 ALDH1A1 (0.46) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL14462928 0.92 SIGMAR1 (0.36) SIGMAR1ALDH1A1HPGDTDP1HSD17B10
SCHEMBL25588356 0.92 ACHE (0.41) SIGMAR1ALDH1A1HPGDTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-20240237514-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2024-07-11 US disclosed
US-20240237514-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2024-07-11 US disclosed
WO-2024039095-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2024-02-22 WO disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023432-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2024-01-18 US disclosed
US-20240023432-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2024-01-18 US disclosed
WO-2023243921-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2023-12-21 WO disclosed
US-4853307-A Imaging member containing a copolymer of styrene and ethyl acrylate XEROX CORPORATION (US) 1989-08-01 US disclosed
US-4764625-A POTASSIUM HYDROXIDE, COPPER CATALYST XEROX CORPORATION (US) 1988-08-16 US disclosed
EP-0149328-B1 MIGRATION IMAGING MEMBER AND METHOD XEROX CORPORATION (US) 1988-06-01 EP disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4233384-A Imaging system using novel charge transport layer XEROX CORPORATION (US) 1980-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 SIGMAR1 4107/4885ALDH1A1 1141/4885HPGD 2774/4885
US-20240023432-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER CYP1B1, NOTUM, CYP4F11 SIGMAR1 2518/4885ALDH1A1 84/4885HPGD 614/4885
US-20240237514-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER CYP1A1, CYP1B1, CYP2E1 SIGMAR1 1068/4885ALDH1A1 16/4885HPGD 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.