SCHEMBL8064124

SCHEMBL8064124

COc1ccc(COCC/C=C/CO)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.49
AGXT P21549 2/20 0.49
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CHRM3 P20309 2/20 0.43
APP P05067 7/20 0.41
CALM1 P0DP23 1/20 0.41
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8064127 1.00 IDO1 (0.49) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL18194682 0.89 L3MBTL1 (0.54) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL12552674 0.85 TDP1 (0.49) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL1030381 0.83 IDO1 (0.52) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL1030380 0.83 IDO1 (0.52) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL12552662 0.80 CNR1 (0.54) IDO1AGXTTDP1L3MBTL1
SCHEMBL16919290 0.79 IDO1 (0.47) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL4741980 0.79 TDP1 (0.54) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL8499580 0.78 IDO1 (0.61) IDO1AGXTTDP1L3MBTL1CA1
SCHEMBL18031455 0.78 ALDH1A1 (0.56) IDO1AGXTTDP1L3MBTL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1026155-A1 VITAMIN D DERIVATIVES AND PROCESS FOR PRODUCING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-08-09 EP disclosed