Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323146 | 0.80 | AKT1 (0.50) | AKT1ALDH1A1RECQLNPC1RAB9A | |
| SCHEMBL8079386 | 0.73 | RIPK1 (0.50) | ALOX5ALDH1A1TSHR | |
| SCHEMBL12265807 | 0.70 | ALOX5 (0.50) | ALOX5HCAR3TRPM8CHRM2CHRM1 | |
| SCHEMBL6235763 | 0.70 | RIPK1 (0.50) | TRPM8ALDH1A1TSHR | |
| SCHEMBL8337464 | 0.70 | GAA (0.43) | ALDH1A1TSHRRECQL | |
| SCHEMBL6436472 | 0.67 | ALOX5 (0.42) | ALOX5HCAR3TRPM8ALDH1A1SLC1A3 | |
| SCHEMBL3878505 | 0.67 | — | — | |
| SCHEMBL8805886 | 0.67 | ALOX5 (0.63) | ALOX5HCAR3TRPM8CHRM2CHRM1 | |
| SCHEMBL20136057 | 0.67 | NPC1 (0.47) | ALOX5ALDH1A1RECQLNPC1RAB9A | |
| SCHEMBL13992431 | 0.67 | ALOX5 (0.46) | ALOX5HCAR3TRPM8CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103721-A | TREATMENT OF STROKE ANOXIA; ANTIHYPERGLYCEMIC,-ISCHEMIC AND -EPILEPTIC AGENTS | ZENECA LIMITED (GB) | 2000-08-15 | — | — | US | disclosed |