Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082541 | 0.86 | MGLL (0.72) | CNR1KIF11MGLLHDAC6 | |
| SCHEMBL30164935 | 0.86 | MGLL (0.72) | CNR1KIF11MGLLHDAC6 | |
| SCHEMBL13749770 | 0.83 | KIF11 (0.69) | FGFR3KDRCNR1KIF11MGLL | |
| SCHEMBL10310335 | 0.83 | CNR1 (0.55) | FGFR3KDRCNR1MGLLMEN1 | |
| SCHEMBL4091879 | 0.83 | CNR1 (0.71) | CNR1KIF11MGLLCNR2 | |
| SCHEMBL5425703 | 0.83 | KIF11 (0.74) | ALDH1A1KIF11MGLLMEN1KMT2A | |
| SCHEMBL28047630 | 0.82 | CFD (0.57) | FGFR3KDRCNR1KIF11MGLL | |
| SCHEMBL28047623 | 0.81 | MGLL (0.51) | FGFR3KDRCNR1ALDH1A1KIF11 | |
| SCHEMBL167713 | 0.80 | MEN1 (0.67) | ALDH1A1MEN1KMT2ATDP1KCNK3 | |
| SCHEMBL11907480 | 0.80 | FGFR3 (1.00) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |