SCHEMBL8064330

SCHEMBL8064330

COc1ccc(S(=O)(=O)c2ccc(C)cc2)cc1S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
POLB P06746 1/20 0.59
MAPK1 P28482 1/20 0.59
GAA P10253 2/20 0.55
SMN1; SMN2 Q16637 4/20 0.54
HTR6 P50406 1/20 0.50
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
TP53 P04637 2/20 0.47
MAPT P10636 1/20 0.47
NAMPT P43490 1/20 0.46
HTT P42858 2/20 0.46
PKM P14618 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18969789 0.89 TSHR (0.54) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL19008830 0.89 TSHR (0.54) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL12276812 0.89 TSHR (0.54) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL8046997 0.86 HTR6 (0.69) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL8064320 0.85 TSHR (0.58) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL19008838 0.85 POLB (0.50) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL12341779 0.84 TSHR (0.61) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL8062009 0.84 KMT2A (0.50) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL17169295 0.82 HTT (0.54) TSHRPOLBMAPK1GAASMN1; SMN2
SCHEMBL25841036 0.82 HTT (0.54) TSHRPOLBMAPK1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed