SCHEMBL8062009

SCHEMBL8062009

COc1ccc(S(=O)(=O)c2cc(C)ccc2C)cc1S(=O)(=O)c1cc(C)ccc1C

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
TSHR P16473 3/20 0.49
POLB P06746 2/20 0.49
MAPK1 P28482 2/20 0.49
MEN1 O00255 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NAMPT P43490 1/20 0.45
RECQL P46063 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.44
CASP1 P29466 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8427164 0.85 KMT2A (0.41) KMT2AUSP2GAASMN1; SMN2TSHR
SCHEMBL8046960 0.84 KMT2A (0.43) KMT2AUSP2GAASMN1; SMN2TSHR
SCHEMBL8064330 0.84 TSHR (0.59) KMT2AUSP2GAASMN1; SMN2TSHR
SCHEMBL8064320 0.83 TSHR (0.58) KMT2AGAASMN1; SMN2TSHRPOLB
SCHEMBL11127859 0.78 GAA (0.60) KMT2AUSP2GAAMEN1L3MBTL1
SCHEMBL6211399 0.78 GAA (0.60) KMT2AUSP2GAATSHRPOLB
SCHEMBL7112755 0.78 UBE2N (0.57) KMT2AGAASMN1; SMN2TSHRLMNA
SCHEMBL11330658 0.77 SMN1; SMN2 (0.44) USP2GAASMN1; SMN2TSHRPOLB
SCHEMBL12834487 0.77 TSHR (0.54) KMT2ASMN1; SMN2TSHRPOLBMAPK1
SCHEMBL8429001 0.76 ALDH1A1 (0.45) KMT2ASMN1; SMN2TSHRPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed