SCHEMBL8046997

SCHEMBL8046997

COc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.69
POLB P06746 2/20 0.59
TSHR P16473 1/20 0.59
MAPK1 P28482 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.54
SFRP1 Q8N474 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 1/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALDH1A1 P00352 2/20 0.47
MAPT P10636 1/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
TP53 P04637 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
PKM P14618 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4618678 0.89 HTR6 (0.58) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL8064330 0.86 TSHR (0.59) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL16797504 0.86 MAPK1 (0.81) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL4616765 0.84 PKM (0.53) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL8061986 0.82 HTR6 (0.46) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL8058697 0.82 HTR6 (0.46) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL6913555 0.82 HTR6 (1.00) HTR6KMT2AKDM4ECA12CA9
SCHEMBL8064320 0.81 TSHR (0.58) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL9633094 0.81 CA1 (0.58) HTR6POLBTSHRMAPK1SMN1; SMN2
SCHEMBL8427238 0.81 HTT (0.51) HTR6POLBTSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US claimed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP claimed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP claimed
JP-9227502-A None JP disclosed
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
JP-H09227502-A SULFONYL COMPOUND AND HEAT-SENSITIVE RECORDING MATERIAL USING THE SAME SANKO CHEM CO LTD 1997-09-02 JP disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed