Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.58 |
| ▸ | METAP2 | P50579 | 3/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181437 | 0.85 | NOS1 (0.55) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL84390 | 0.81 | MAPT (0.60) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL18559548 | 0.78 | MAPT (0.55) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL18737272 | 0.78 | MAPT (0.50) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL3722916 | 0.78 | MAPT (0.54) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL21510145 | 0.78 | MAPT (0.50) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL6202977 | 0.78 | NOS1 (0.50) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL14534860 | 0.77 | MAPT (0.49) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL14072852 | 0.75 | ALDH1A1 (0.48) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL27735950 | 0.74 | DYRK1A (0.46) | NOS1METAP2DYRK1AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056834-C | Novel arylindazoles and their use as herbicides | ZENECA LTD (GB) | 2000-09-27 | — | — | CN | disclosed |
| EP-0630367-B1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LTD (GB) | 2000-07-05 | — | — | EP | disclosed |
| US-5928998-A | PRE- AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| US-5444038-A | Arylindazoles and their use as herbicides | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| EP-0630367-A1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| CN-1079961-A | New arylindazoles and they are as the purposes of weedicide | SERIAL (GB) | 1993-12-29 | — | — | CN | disclosed |
| WO-1993018008-A1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |