Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibromoacetic Acid SCHEMBL8047059 | 0.90 | THRB (0.46) | RORCTHRBTHRACYP2D6MEN1 | |
| SCHEMBL8057619 | 0.78 | RORC (0.46) | RORCTHRBTHRA | |
| Dibromoacetic Acid SCHEMBL8059529 | 0.78 | THRB (0.51) | THRBTHRA | |
| SCHEMBL8062096 | 0.77 | THRB (0.45) | RORCTHRBTHRACYP2D6HTT | |
| SCHEMBL8047083 | 0.76 | THRB (0.47) | RORCTHRBTHRASCN1ASCN2A | |
| SCHEMBL7050847 | 0.74 | THRB (0.54) | RORCTHRBTHRA | |
| SCHEMBL8047080 | 0.73 | THRB (0.50) | THRBTHRA | |
| SCHEMBL8064350 | 0.71 | THRB (0.47) | THRBTHRA | |
| Dichloroacetic Acid SCHEMBL4351126 | 0.71 | THRB (0.51) | THRBTHRA | |
| SCHEMBL7074480 | 0.70 | RORC (0.45) | RORCTHRBTHRALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000008-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999000353-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 1999-01-07 | — | — | WO | disclosed |