Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047080 | 0.92 | THRB (0.50) | THRBTHRA | |
| Dichloroacetic Acid SCHEMBL4351126 | 0.90 | THRB (0.51) | THRBTHRA | |
| SCHEMBL8064350 | 0.90 | THRB (0.47) | THRBTHRA | |
| Dibromoacetic Acid SCHEMBL8047059 | 0.88 | THRB (0.46) | THRBTHRA | |
| SCHEMBL8059520 | 0.85 | THRB (0.49) | THRBTHRA | |
| SCHEMBL8057622 | 0.83 | THRB (0.42) | THRBTHRA | |
| SCHEMBL8058793 | 0.80 | THRA (0.43) | THRBTHRA | |
| SCHEMBL8064359 | 0.78 | RORC (0.43) | THRBTHRA | |
| SCHEMBL8058810 | 0.73 | THRA (0.58) | THRBTHRA | |
| SCHEMBL8057619 | 0.73 | RORC (0.46) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000008-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 2000-05-17 | — | — | EP | claimed |
| WO-1999000353-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 1999-01-07 | — | — | WO | claimed |
| EP-1000008-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999000353-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 1999-01-07 | — | — | WO | disclosed |