Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29186041 | 0.89 | CDK1 (0.44) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL8066879 | 0.82 | GSK3B (0.46) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL28085134 | 0.82 | CDK1 (0.45) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL29270987 | 0.81 | CDK1 (0.44) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL13829395 | 0.81 | CDK1 (0.44) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL1164884 | 0.81 | ALDH1A1 (0.50) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL1164995 | 0.81 | ALDH1A1 (0.50) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL8063267 | 0.80 | GSK3B (0.49) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL7030025 | 0.79 | LMNA (0.48) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL4129050 | 0.78 | CDK1 (0.47) | CDK1CCNB1GSK3AGSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |