Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.50 |
| ▸ | CES1 | P23141 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055152 | 0.84 | POLB (0.55) | CES2CES1NPC1RAB9AHPGD | |
| SCHEMBL8609889 | 0.84 | HPGD (0.61) | NPC1RAB9AHPGDKDM4ECYP1A2 | |
| SCHEMBL8065520 | 0.83 | CES2 (0.56) | CES2CES1NPC1RAB9A | |
| SCHEMBL11764098 | 0.77 | CES2 (0.58) | CES2CES1NPC1RAB9AHPGD | |
| SCHEMBL9749593 | 0.76 | CES1 (0.62) | CES2CES1NPC1RAB9AHPGD | |
| SCHEMBL6352999 | 0.76 | CES2 (0.52) | CES2CES1RAB9A | |
| SCHEMBL8609175 | 0.75 | KDM4E (0.59) | NPC1RAB9AHPGDKDM4ECYP1A2 | |
| SCHEMBL2225523 | 0.75 | CES2 (0.78) | CES2CES1NPC1RAB9AHPGD | |
| SCHEMBL29468149 | 0.75 | CES2 (0.78) | CES2CES1NPC1RAB9AHPGD | |
| SCHEMBL1977726 | 0.75 | CES2 (0.78) | CES2CES1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596395-B1 | Process for the preparation of fluorinated benzil | CLARIANT GMBH (DE) | 2000-06-28 | — | — | EP | disclosed |
| US-5463135-A | Fluorinated benzils and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0596395-A1 | Fluorinated benzils and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | EP | disclosed |