Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153076 | 1.00 | AMY1A (0.50) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL3960601 | 0.82 | GABRA1 (0.66) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL5159444 | 0.81 | GABRA1 (0.65) | GABRA1GABRB2TRPA1TP53TDP1 | |
| SCHEMBL15666913 | 0.81 | AMY1A (0.53) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL15666912 | 0.81 | AMY1A (0.53) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL23049820 | 0.81 | NR3C1 (0.48) | TDP1HTTALDH1A1HPGDGAA | |
| SCHEMBL15667381 | 0.81 | AMY1A (0.53) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL14478234 | 0.79 | AMY1A (0.52) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL5271763 | 0.78 | AMY1A (0.41) | AMY1AGABRA1GABRB2TRPA1TP53 | |
| SCHEMBL17500128 | 0.77 | CYP2D6 (0.54) | GABRA1GABRB2TDP1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036253-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE. | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-03-22 | — | — | WO | disclosed |