Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219083 | 0.87 | TAS1R3 (0.44) | MAPTALDH1A1MAPK1LMNATAS1R3 | |
| SCHEMBL8064735 | 0.79 | ESR1 (0.47) | ALDH1A1HPGDLMNA | |
| SCHEMBL29175992 | 0.78 | ALDH1A1 (0.35) | RAB9AMAPTALDH1A1HPGDMAPK1 | |
| Hydrogen Peroxide SCHEMBL9456643 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLB | |
| SCHEMBL29136222 | 0.69 | ESR1 (0.50) | ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL10699158 | 0.68 | CYP3A4 (0.50) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL6057016 | 0.68 | POLB (0.38) | MAPTALDH1A1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL128091 | 0.67 | NPC1 (0.81) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL5495193 | 0.67 | SMN1; SMN2 (0.53) | ALDH1A1MAPK1POLBLMNASMN1; SMN2 | |
| SCHEMBL11795050 | 0.67 | ESR1 (0.47) | ALDH1A1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005514-A1 | LIQUID CURABLE RESIN COMPOSITION | DSM N.V. (NL) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010443-A1 | LIQUID CURABLE RESIN COMPOSITION | DSM N.V. (NL) | 1999-03-04 | — | — | WO | disclosed |