Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064735 | 0.79 | ESR1 (0.47) | ALDH1A1HSD17B10CYP3A4TSHRLMNA | |
| SCHEMBL8064733 | 0.78 | NPC1 (0.43) | ALDH1A1MAPTMAPK1SMN1; SMN2GRIA4 | |
| Hydrogen Peroxide SCHEMBL9456643 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL29219083 | 0.76 | TAS1R3 (0.44) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL12190490 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL12190487 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL29136222 | 0.69 | ESR1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL6057016 | 0.68 | POLB (0.38) | ALDH1A1MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL292857 | 0.67 | RAB9A (0.47) | ALDH1A1MAPTMAPK1SMN1; SMN2HSD17B10 | |
| SCHEMBL11795050 | 0.67 | ESR1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260738-B | Thermo-oxidative-resistant thermoplastic polyurethane and preparation method thereof | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |