Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210438 | 0.86 | CHIT1 (0.35) | DRD2HTR3AHRH4CHIT1CHIA | |
| SCHEMBL186581 | 0.83 | CCR1 (0.35) | DRD2HTR3AHRH4CHIT1CHIA | |
| SCHEMBL7708685 | 0.83 | CCR1 (0.34) | DRD2HTR3AHRH4SCN9ACCR1 | |
| SCHEMBL187793 | 0.83 | CCR1 (0.34) | DRD2HTR3AHRH4SCN9ACCR1 | |
| SCHEMBL15800089 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A | |
| SCHEMBL12921440 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A | |
| SCHEMBL972213 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A | |
| SCHEMBL15088390 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A | |
| SCHEMBL12208780 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A | |
| SCHEMBL15088377 | 0.83 | CHIT1 (0.35) | DRD2HTR3ACHIT1CHIASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |