Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068258 | 0.90 | EPHX2 (0.40) | KMT2AMEN1LMNAGAAMAPT | |
| SCHEMBL8066365 | 0.87 | POLB (0.38) | KMT2AMEN1HTTPOLB | |
| SCHEMBL4539368 | 0.86 | KMT2A (0.46) | KMT2AMEN1ALDH1A1FBP1LMNA | |
| SCHEMBL8066441 | 0.83 | BDKRB1 (0.42) | KMT2AMEN1ALDH1A1HSD11B1 | |
| SCHEMBL4535853 | 0.82 | FBP1 (0.46) | KMT2AMEN1ALDH1A1FBP1LMNA | |
| SCHEMBL4536850 | 0.81 | EPHX1 (0.52) | KMT2AMEN1ALDH1A1FBP1LMNA | |
| SCHEMBL4540834 | 0.77 | HSD11B1 (0.47) | KMT2AMEN1ALDH1A1FBP1HSD11B1 | |
| SCHEMBL4540068 | 0.77 | EPHX1 (0.54) | FBP1LMNAHSD11B1HTT | |
| SCHEMBL8062169 | 0.76 | FBP1 (0.50) | KMT2AMEN1ALDH1A1FBP1LMNA | |
| SCHEMBL4542443 | 0.76 | FBP1 (0.50) | KMT2AMEN1ALDH1A1FBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |