SCHEMBL8065205

SCHEMBL8065205

CC(C)CCOc1ccc(Cl)c2c1[S+]([O-])c1ccccc1C2

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.32
TLR8 Q9NR97 1/20 0.32
IDO1 P14902 1/20 0.31
MCHR1 Q99705 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133173 0.87 CSNK2A1 (0.35)
SCHEMBL1615176 0.84 S1PR5 (0.36) NPSR1TLR8
SCHEMBL3159501 0.84 S1PR5 (0.36) NPSR1TLR8
SCHEMBL84111 0.82 MEN1 (0.30)
SCHEMBL1614837 0.82 S1PR1 (0.32)
SCHEMBL1615143 0.80 NPC1 (0.38)
SCHEMBL7769310 0.80 PTPRC (0.30)
SCHEMBL8074840 0.79 ADRA2A (0.45)
SCHEMBL6493951 0.78 TDP1 (0.40)
SCHEMBL8065187 0.76 MEN1 (0.39) HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520574-B1 Thioxanthone derivatives LAMBSON FINE CHEMICALS LIMITED (GB) 2000-08-16 EP disclosed
US-5414092-A Photoinitiators INTERNATIONAL BIO-SYNTHETICS LIMITED (GB) 1995-05-09 US disclosed
EP-0520574-A1 Thioxanthone derivatives GREAT LAKES FINE CHEMICALS LIMITED (GB) 1992-12-30 EP disclosed